What Clotting Factor Is Deficient in Von Willebrand Disease? Understanding VWF and its Role
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3 min read
Affecting up to 1% of the U.S. population, von Willebrand disease (VWD) is the most common inherited bleeding disorder. At the heart of this condition is a problem with blood clotting, making the question of **what clotting factor is deficient in von Willebrand disease** central to understanding its effects. The primary issue is with the von Willebrand factor (VWF) itself, though this can also indirectly lead to a deficiency of another key clotting protein, Factor VIII (FVIII).