Category: Bone disorders

While most bone formation, or ossification, is a normal developmental process, certain medical conditions cause bone to form in places it shouldn't. This abnormal, or heterotopic, ossification can stem from genetic mutations, severe trauma, or certain neurological injuries, leading to debilitating symptoms and limited mobility.

Chronic hemolytic anemia, a hallmark of sickle cell anemia, triggers the body's bone marrow to work overtime to produce red blood cells. This intensive process can cause significant skeletal abnormalities, making it crucial to understand **what are the skull changes in sickle cell anemia** and their clinical significance.

Affecting up to 1 million people in the United States alone, Paget's disease of bone is a chronic disorder that disrupts your body's natural bone renewal cycle. This condition leads to bones that are weak, enlarged, and prone to fracture, though many people with the disease may not experience noticeable symptoms.