Category: Connective tissue diseases

Affecting an estimated 50 to 300 people per million, systemic sclerosis (SSc), also known as scleroderma, is a rare autoimmune disease that attacks the internal organs by causing an overproduction of collagen. This condition can lead to widespread scarring and thickening (fibrosis) that can severely impact organ function and quality of life.

According to the Marfan Foundation, Beals syndrome is a disorder of connective tissue caused by a mutation in the FBN2 gene. Also known as Congenital Contractural Arachnodactyly (CCA), this condition affects skeletal development, causing distinct features such as multiple joint contractures and a characteristic physical appearance.

According to the National Scleroderma Foundation, around 300,000 Americans have scleroderma, the disease that causes your body to harden. This autoimmune condition leads to the overproduction of collagen, resulting in fibrous, tight, and sometimes life-threatening tissue.

Marfan syndrome affects approximately 1 in 5,000 people, but its wide-ranging symptoms can vary drastically from person to person. Understanding **what are symptoms associated with Marfan syndrome?** is crucial for early diagnosis and effective management of this complex genetic disorder.