Category: Drug metabolism

Research indicates that THC metabolites can be detected in a chronic, heavy user's system for over 30 days via a urine test. For a potent dose like a 420 mg edible, the duration it stays in your system is influenced by a complex interplay of biological factors and consumption habits.

According to pharmacokinetic principles, the elimination half-life of a drug is fundamentally determined by the interplay between its clearance (CL) and its volume of distribution (VD). Understanding **what is the relationship between clearance and VD** is therefore crucial for predicting a drug's duration of action and designing safe and effective dosing regimens. While independent parameters, their combined effect dictates how long a drug remains active in the body.