Category: Rare blood types

Worldwide, a blood type known as Rh-null is one of the most difficult to source, with fewer than 50 known cases ever reported globally [4]. It is often referred to as “golden blood” because of its extraordinary rarity, directly addressing the query about what is the hardest blood type to get donor [4].

With more than 40% of Americans having O+ blood, its commonness is a stark contrast to the world's rarest types. For those with exceptionally rare blood, knowing **what is the hardest blood to donate?** is a matter of life-or-death, impacting the speed and reliability of crucial transfusions.