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Do any illnesses start with a headache? Understanding the warning signs

4 min read

While most headaches are temporary and harmless, a new or unusual headache can sometimes signal an underlying health issue. This makes it crucial to understand the context of your pain when considering the question: Do any illnesses start with a headache?

Quick Summary

A headache can certainly be the initial sign of a wide array of medical conditions, ranging from common viral infections to potentially severe neurological or systemic diseases. Paying attention to other accompanying symptoms and the headache's specific characteristics is key to determining its cause.

Key Points

  • Initial Symptom: Yes, a headache can be the very first sign of an underlying illness, ranging from mild infections to severe neurological conditions.

  • Secondary vs. Primary: A headache that signals another illness is called a secondary headache, distinct from primary headaches like migraines, where the pain itself is the primary problem.

  • Infectious Causes: Infections such as meningitis, encephalitis, and even viral illnesses like COVID-19 can begin with a headache, sometimes before other symptoms appear.

  • Emergency Indicators: Seek immediate medical help for 'thunderclap' headaches (the worst you've ever had) or headaches accompanied by fever, stiff neck, vision changes, or confusion.

  • Neurological Risks: More serious causes include brain aneurysms, tumors, or inflammation of the arteries, and require prompt medical evaluation.

  • Not Just Brain-Related: Systemic issues like very high blood pressure, sleep apnea, and even carbon monoxide poisoning can also manifest initially as a headache.

In This Article

What is a Secondary Headache?

Headaches are broadly categorized into primary and secondary types. Primary headaches, such as migraines, tension-type, and cluster headaches, are not caused by an underlying illness. The headache itself is the condition. A secondary headache, however, is a symptom caused by another medical condition, which can sometimes be the first or even the sole manifestation of the problem. Recognizing the difference and understanding the red flags associated with secondary headaches can be lifesaving.

Infectious Diseases

Infections are a common cause of secondary headaches. While many systemic viral infections, like influenza, can cause a headache, it is typically accompanied by other symptoms like fever and body aches. In certain, more severe cases, a headache can be the most prominent and initial symptom.

  • Meningitis: This is an infection and inflammation of the membranes (meninges) surrounding the brain and spinal cord. For intracranial infections like bacterial meningitis, the headache is often the first symptom and can be severe and progressive, accompanied by fever, neck stiffness, and confusion.
  • Encephalitis: Inflammation of the brain itself can also present with a headache, often alongside fever, seizures, or changes in consciousness.
  • COVID-19: As seen in the recent pandemic, a headache can be one of the earliest or even the only symptom of a SARS-CoV-2 infection. Some COVID-related headaches have been reported as moderate-to-severe, bilateral, and resistant to typical painkillers.
  • Lyme Disease: In the early stages, this tick-borne illness can cause nonspecific symptoms, including a headache, before other signs like a rash appear.

Neurological and Vascular Conditions

Some of the most critical illnesses that begin with a headache involve the brain and its blood vessels. These conditions often require immediate medical attention.

Vascular Events

  • Brain Aneurysm: This is a weak spot in a blood vessel that balloons and can rupture, causing a subarachnoid hemorrhage. A ruptured aneurysm is often characterized by a 'thunderclap' headache, described as the worst headache of your life, reaching maximum intensity within seconds or minutes.
  • Cerebral Venous Sinus Thrombosis (CVST): This is a rare condition involving a blood clot in the brain's venous sinuses. Headache is the most common symptom, which can be progressive and diffuse, worsening over time.
  • Giant Cell Arteritis (Temporal Arteritis): This inflammatory condition of the arteries, often affecting those over 50, can cause a new, severe headache, especially near the temples, and may be accompanied by jaw pain or vision loss.

Other Neurological Issues

  • Brain Tumor: While rare, a new or worsening headache can be a symptom of a brain tumor, especially if it increases in frequency and severity.
  • Idiopathic Intracranial Hypertension (Pseudotumor Cerebri): This condition involves increased pressure inside the skull without a known cause. It can cause chronic, daily headaches and visual disturbances.

Systemic and Other Causes

A headache can also be the initial sign of problems elsewhere in the body.

  • Acute Sinusitis: Inflammation or infection of the sinuses can cause pressure and pain in the forehead, cheeks, or around the eyes.
  • High Blood Pressure (Hypertension): In cases of hypertensive crisis, when blood pressure spikes to dangerously high levels, a headache is a common symptom.
  • Obstructive Sleep Apnea (OSA): Many people with OSA experience headaches upon waking, caused by low oxygen levels and high carbon dioxide levels during sleep.
  • Carbon Monoxide Poisoning: Exposure to this toxic gas can cause a headache as one of the first signs.
  • Preeclampsia: This pregnancy-related condition involving high blood pressure often starts with a new or persistent headache.

How to Tell the Difference: Benign vs. Serious Headaches

It's important to know the difference between a normal headache and one that warrants concern. This table compares common headache features to those that act as potential warning signs.

Feature Typical, Benign Headache Potential Warning Sign (Red Flag)
Onset Gradual, often predictable Sudden, explosive 'thunderclap' onset
Severity Mild to moderate pain Extreme, debilitating pain (worst ever)
Pattern Stable, familiar type New type of headache, or increasing frequency/intensity
Accompanying Symptoms May include nausea or sensitivity to light Fever, stiff neck, confusion, seizure, vision changes, loss of balance
Triggers Stress, dehydration, fatigue Sudden physical exertion, coughing, sneezing
Age of Onset Any age New-onset headache after age 50
Response to Treatment Responds well to over-the-counter medication Resistant to usual pain relievers

When to Seek Medical Attention

While most headaches are not cause for alarm, certain symptoms should prompt immediate medical evaluation. You should seek emergency care if you experience a severe or sudden headache, especially if it's the worst you've ever had, or if it is accompanied by any of the "red flag" symptoms listed above. For new or persistent headaches without emergency features, it is still advisable to see your doctor for an accurate diagnosis.

Conclusion

Headaches can be the first clue to a more serious medical condition, so it's vital to pay attention to your body and recognize the signs. Keeping track of headache patterns and accompanying symptoms can provide your healthcare provider with valuable information for an accurate diagnosis. While scary, the most severe causes are rare. However, understanding when a headache might be a warning sign is a key step toward protecting your health. Always consult a healthcare professional for a proper diagnosis and treatment plan, as self-diagnosis can be dangerous. For more information, visit the Mayo Clinic's Headache page.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Consult a healthcare professional for diagnosis and treatment.

Frequently Asked Questions

Yes, in some cases, particularly with certain viral infections like COVID-19, a headache can be the only initial symptom a person experiences, at least for a period of time.

You should be concerned and seek immediate medical care if you experience a 'thunderclap' headache (sudden, severe), a new headache after age 50, a headache with fever and stiff neck, or a headache following a head injury.

A primary headache, such as a migraine, is the condition itself. A secondary headache is a symptom caused by another underlying medical issue, like an infection, a tumor, or a vascular problem.

Yes, it is very common for people to mistake migraines for sinus headaches, as both can cause pressure and pain in the face. Migraines can also present with nasal congestion. A doctor can help determine the correct diagnosis.

Intracranial infections like meningitis and encephalitis often begin with a headache. Systemic viral infections like the flu and COVID-19 also commonly cause headaches early on.

No, a headache with a fever is a common symptom of many non-serious viral infections, like the flu. However, when combined with other "red flags" like a stiff neck, it can indicate a more serious condition like meningitis.

Stress can cause tension headaches, which can sometimes be severe and alarming. However, it's the specific pattern, onset, and accompanying symptoms (or lack thereof) that help differentiate a stress headache from one caused by a more dangerous underlying condition.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.