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How common is cannabinoid hyperemesis syndrome? Understanding the increasing prevalence

4 min read

Based on emergency department surveys, cannabinoid hyperemesis syndrome (CHS) is estimated to affect around 2.75 million people in the US yearly, a number that has been steadily increasing. This condition, associated with chronic and heavy cannabis use, is becoming more widely recognized within the medical community and among users.

Quick Summary

The exact prevalence of cannabinoid hyperemesis syndrome (CHS) is still not definitively known due to underdiagnosis, but evidence suggests it is far from rare among heavy, long-term cannabis users, with cases increasing as cannabis use rises. Estimates from emergency department data indicate millions of people in the US may be affected annually, highlighting its growing public health significance.

Key Points

  • Prevalence is Rising: Recent emergency department surveys estimate CHS affects about 2.75 million people in the US annually, with cases increasing as cannabis use and potency rise.

  • High-Risk Group: The syndrome primarily impacts heavy, long-term cannabis users, particularly young adults aged 18 to 39.

  • Misdiagnosis is Common: CHS is often mistaken for other gastrointestinal disorders, such as cyclic vomiting syndrome, delaying proper treatment.

  • Cessation is the Cure: The only permanent solution for CHS is to completely stop using cannabis; symptoms will recur with continued use.

  • Higher Potency is a Factor: The increased concentration of THC in modern cannabis products is a significant contributing factor to the rising number of CHS cases.

  • Hot Showers Offer Temporary Relief: A classic, if paradoxical, symptom is that hot baths or showers provide temporary relief from the intense nausea and vomiting.

In This Article

Understanding the growing concern of CHS

Cannabinoid Hyperemesis Syndrome (CHS) is a condition that causes severe, cyclical episodes of nausea, vomiting, and abdominal pain in chronic, heavy cannabis users. While initially considered rare after it was first described in 2004, its recognition and incidence have surged, particularly in areas where cannabis has been legalized. The increasing potency of THC in modern cannabis products is a significant contributing factor to this trend. The syndrome is often misdiagnosed as cyclic vomiting syndrome or other gastrointestinal issues, which can lead to delayed treatment and repeated, costly hospital visits.

Why is CHS becoming more common?

Several factors contribute to the rising number of CHS cases observed in emergency departments and clinics:

  • Increased access and use: The legalization of cannabis in many regions has led to an overall increase in both the number of users and the frequency of use. This broader access means more people are engaging in the heavy, long-term use patterns that are a prerequisite for developing CHS.
  • Higher THC potency: The concentration of delta-9-tetrahydrocannabinol (THC) in cannabis products has climbed dramatically over the years. Higher potency products are more likely to disrupt the body's endocannabinoid system, a key factor in the development of CHS.
  • Greater awareness: As the medical community becomes more aware of CHS, healthcare providers are better equipped to recognize and diagnose it. Increased understanding of the syndrome's link to chronic cannabis use helps differentiate it from other conditions, leading to more accurate reporting.
  • Demographic shifts: Studies show that CHS is particularly prevalent among young adults, typically aged 18 to 39, a demographic that is also a significant consumer of cannabis. Increases in cannabis use within this age group directly correlate with a higher incidence of CHS.

Who is most at risk for CHS?

While not every heavy cannabis user will develop CHS, certain risk factors increase an individual's susceptibility:

  • Long-term, heavy use: This is the most crucial risk factor. CHS typically occurs in individuals who use cannabis daily or multiple times per day for at least a year.
  • Age: Young adults, particularly males aged 16 to 34, appear to be at a higher risk.
  • Early initiation: Starting cannabis use at a younger age, such as before 16, may increase the risk.
  • High THC concentration: Consistent use of high-potency cannabis products is strongly linked to CHS development.
  • Other substance use disorders: Individuals with other substance use issues or those who smoke cigarettes may also have higher rates of CHS.

CHS vs. Cyclic Vomiting Syndrome: A comparison

CHS is often misidentified as Cyclic Vomiting Syndrome (CVS), a condition with similar symptoms but different underlying causes and treatment paths. Differentiating between the two is crucial for effective treatment.

Feature Cannabinoid Hyperemesis Syndrome (CHS) Cyclic Vomiting Syndrome (CVS)
Trigger Heavy, chronic cannabis use Unknown, but stress and anxiety can be triggers
Symptom Relief Temporarily relieved by hot baths or showers; permanent relief with cannabis cessation Not typically responsive to cannabis cessation; may require medication to manage symptoms
Demographics Primarily affects heavy, long-term cannabis users, often young adults Can affect individuals of any age, including children
Gastrointestinal Symptoms Severe nausea, abdominal pain, and bouts of vomiting Severe nausea and vomiting
Treatment Discontinuation of cannabis is the definitive cure Focuses on symptom management and identifying triggers

Diagnosis and long-term outlook

Diagnosing CHS can be a challenge. It typically involves a careful review of the patient's history of cannabis use, their specific symptom pattern, and the response to treatment. The key diagnostic criteria often include:

  1. A history of chronic, heavy cannabis use.
  2. Recurrent episodes of severe nausea and vomiting.
  3. Relief of symptoms by taking hot showers or baths.
  4. Complete resolution of symptoms after discontinuing cannabis use.

The long-term prognosis for CHS is excellent, provided that the individual abstains from cannabis. Continued use will inevitably lead to recurring symptoms and potential complications, such as dehydration, electrolyte abnormalities, dental erosion, or even acute kidney injury. For those struggling with cessation, treatment options are available to help manage symptoms and support recovery, including antiemetics and psychosocial interventions. For more information on managing substance use disorders, consider visiting the resources at the National Institute on Drug Abuse (NIDA).

The takeaway

While not everyone who uses cannabis will experience CHS, the syndrome is far from rare among heavy users and is becoming increasingly common. The rise in cases correlates with higher THC potency and broader cannabis legalization. Awareness of CHS is vital for both users and healthcare professionals to ensure prompt diagnosis and, most importantly, for affected individuals to understand that ceasing cannabis use is the definitive cure. Recognizing the signs of CHS is the first step toward effective management and recovery from this painful condition.

Frequently Asked Questions

While the exact figure is unclear, one 2018 study found that nearly a third (32.9%) of self-reported frequent marijuana users visiting the emergency room met the criteria for CHS. This suggests the condition is significantly more common than previously assumed among this specific group.

The increase in CHS cases is linked to several factors, including the legalization of recreational cannabis, which has led to increased usage, and the widespread availability of high-potency cannabis products with elevated THC concentrations. Growing medical awareness also contributes to more accurate diagnoses.

No, CHS is primarily associated with chronic and heavy cannabis use, typically daily or multiple times per day, over a long period (often more than one year). Occasional or light users are not generally at risk.

Key symptoms include recurrent and severe episodes of nausea, abdominal pain, and vomiting. A hallmark sign is the temporary relief of these symptoms with hot baths or showers.

Although anyone using cannabis can develop CHS, research indicates it is most common among young adults aged 18 to 39. Studies have also noted higher rates among males aged 16 to 34.

The most important step is to stop all cannabis use immediately. While symptoms may persist for some time, this is the only definitive cure. A consultation with a healthcare provider is also recommended for proper diagnosis, symptom management, and support.

Yes, CHS is treatable, but the permanent solution requires complete abstinence from cannabis. Supportive care in the emergency room often includes intravenous fluids for dehydration, but conventional anti-nausea medications are often ineffective.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.