Tag: Apert syndrome

Affecting approximately 1 in 20,000 births, orbital hypertelorism is the medical term for having abnormally wide-set eyes. However, this is not a syndrome itself but a physical symptom of many underlying congenital disorders. Understanding **what syndrome causes wide eyes** is crucial for proper diagnosis and management, as the associated conditions can impact overall health and development.

According to studies, congenital anomalies affecting craniofacial development occur in approximately 2–3% of all newborns. A midfacial hypoplasia is a developmental condition characterized by the underdevelopment of the bones and tissues in the middle third of the face. This can result in distinctive facial features and, in more severe cases, significant functional problems.

Affecting approximately 1 in every 65,000 to 88,000 newborns, Apert syndrome is a rare genetic disorder caused by a mutation in the *FGFR2* gene, which leads to distinct physical characteristics. The condition, therefore, presents with a specific and recognizable face of Apert syndrome that is a key diagnostic feature.