Understanding the Paradox: Why Does Bleeding Occur in Essential Thrombocythemia?
•
5 min read
Essential thrombocythemia (ET), a rare myeloproliferative neoplasm, can paradoxically increase the risk of both clotting and bleeding. This counterintuitive dual risk challenges the assumption that high platelet counts always lead to increased coagulation. The key to understanding why does bleeding occur in essential thrombocythemia lies in the dysfunctional nature of the overproduced platelets and secondary clotting factor deficiencies.