Tag: Bernard soulier syndrome

According to the National Institutes of Health, platelets are crucial for stopping bleeding. A person with a platelet aggregation defect has blood platelets that do not properly clump together, impairing the vital blood clotting process and increasing the risk of excessive bleeding.

Giant platelets, also known as macrothrombocytes, are a key feature of several rare inherited bleeding disorders known as macrothrombocytopenias. The most well-known disease associated with giant platelets is Bernard-Soulier syndrome (BSS), which impairs blood clotting and can lead to excessive bleeding.

Giant platelets, known as macrothrombocytes, are platelets with a diameter greater than 7 microns, significantly larger than normal platelets. The presence of these abnormally large blood cells, a condition called macrothrombocytopenia, can indicate several underlying diseases, both inherited and acquired.