Tag: Bombay blood group

Worldwide, a blood type known as Rh-null is one of the most difficult to source, with fewer than 50 known cases ever reported globally [4]. It is often referred to as “golden blood” because of its extraordinary rarity, directly addressing the query about what is the hardest blood type to get donor [4].

While AB-negative is the rarest of the eight major blood types in some populations, the three rarest phenotypes in the world are far more extraordinary. These extremely rare blood groups, caused by specific genetic mutations, present unique challenges for transfusion medicine. This article details what are the three rarest blood types.