Tag: Diagnosis of exclusion

Approximately 1 in 10 Americans live with a rare disease, and many such illnesses fall under the category of idiopathic, meaning their cause is unknown. This guide explores **what diseases have no known cause**, delving into the medical terminology and latest research surrounding these baffling conditions.

Medical research indicates that between 84% and 91% of Americans with Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), remain undiagnosed. This alarming statistic reflects the complexity of the illness and confirms that an accurate diagnosis requires professional medical expertise, making it impossible to confidently **can you self-diagnose CFS?**.

Statistics indicate that Superior Mesenteric Artery Syndrome (SMAS) has a worldwide incidence of just 0.1-0.3%, confirming that **is SMAS a rare disease?** Yes, it is. This is a severe but often overlooked gastrointestinal condition that results from anatomical compression of the small intestine.

The term 'idiopathic' is used in medicine to describe a disease with no known cause, which accounts for a significant number of diagnoses. When clinicians have ruled out all other identifiable factors, the condition is classified as being of unknown origin. This article explains what is a medical condition that has no known cause and explores its impact.