Tag: Drug metabolism

While most patients wake up within minutes of general anesthesia ending, a phenomenon called delayed emergence can occur in some cases, with studies suggesting that failure to regain consciousness within 30-90 minutes warrants observation. If you are wondering, **why is my anesthesia taking so long to wear off?**, the reasons can range from individual patient factors to the specific medications used during your procedure.

According to the American Society of Anesthesiologists (ASA), patients who smoke are at a significantly higher risk for complications during and after surgery. This is because **nicotine affects sedation** in complex and multifaceted ways, impacting not only the required dose but also the overall safety of the procedure.

Studies suggest that genetic factors can account for a significant portion of the variability in how a person responds to a substance, sometimes as much as 95%. The answer to, **Can you be born with a high tolerance?**, lies in a fascinating interplay between inherited traits and a body's inherent baseline sensitivity to various compounds.

According to the National Institutes of Health (NIH), a drug's effectiveness can be significantly altered by its first-pass metabolism, a critical concept in pharmacology. Understanding **what is a first pass assessment** is therefore essential, as the term encompasses two different but important processes within the field of general health. These distinct meanings relate to pharmacology and to initial risk screening.

The body's blood volume is approximately 7% of a person's total body weight, circulating continuously and acting as the main transport system for chemicals and compounds throughout the body. A substance's stay in your body is influenced by many variables, making a simple answer to the question, 'How long does stuff stay in your bloodstream?', quite complex.

Did you know that depending on the method of consumption, the peak of a high can range from minutes to several hours? Understanding the stages of a high, and especially **what is the peak of a high**, is crucial for anyone using cannabis, as it allows for a more predictable and safer experience.