Tag: Fbn1 gene

Affecting an estimated 1 in 5,000 to 10,000 people globally, Marfan syndrome is a genetic disorder of the body's connective tissue. Understanding **who is most likely to have Marfan syndrome** requires looking at both family history and spontaneous genetic changes.

Affecting approximately 1 in 5,000 people, Marfan syndrome is a genetic disorder caused by a mutation in the *FBN1* gene that weakens connective tissue throughout the body. Understanding **what are the three most commonly affected organ systems in Marfan syndrome** is vital for early diagnosis and effective management, particularly given the potential for life-threatening complications.