Tag: Genetic mosaicism

Affecting less than 1 in 22,313 live births, PIK3CA-Related Overgrowth Spectrum (PROS) is a rare genetic condition. The prognosis for PIK3CA overgrowth syndrome is highly variable, depending on the severity and location of the overgrowth.

With a global incidence of less than 1 in 1 million people, Proteus syndrome is one of the rarest genetic disorders in the world. In response to the question, 'Does Proteus syndrome still exist?', the definitive answer is yes; although rare, new cases continue to be diagnosed.

Ollier's disease, a very rare bone disorder characterized by multiple benign cartilage growths (enchondromas), is estimated to affect around 1 in 100,000 people. Based on current world population data, this suggests that the disease affects tens of thousands of individuals worldwide, although mild cases may go undiagnosed.

With its highly variable prognosis, Proteus syndrome, a rare genetic disorder, is a complex condition to predict outcomes for. A significant risk of early mortality exists due to life-threatening complications, making the question, 'What is the life expectancy of someone with Proteus disease?' a critical one for affected individuals and their families.

Affecting fewer than 1 in 1 million people worldwide, Proteus syndrome is a profoundly rare genetic condition. This progressive disorder causes the asymmetric, disproportionate overgrowth of various tissues, including bones, skin, and organs, presenting unique challenges for those affected.