Tag: Inherited disorders

Affecting up to one percent of the global population, von Willebrand disease (VWD) is the most common inherited coagulopathy. Despite its prevalence, many people with mild forms of the condition remain undiagnosed due to the subtlety of their symptoms. This guide explains everything you need to know about the most common coagulopathy.

According to estimates based on data from the Centers for Disease Control and Prevention (CDC), approximately 7,000 individuals are affected by **hemophilia B** in the United States. This makes it significantly less common than hemophilia A, though both are rare, inherited bleeding disorders that require lifelong medical management. The precise number can be challenging to ascertain due to variations in data collection and reporting.

Affecting approximately 1 in 5,000 male births in the United States, hemophilia A is a rare genetic bleeding disorder. A common question that arises is **what is hemophilia A also known as?**; it is widely known as classic hemophilia or Factor VIII deficiency. This condition results from a missing or defective clotting protein, Factor VIII, which is crucial for proper blood clotting.

Affecting approximately 1 in 2,500 individuals, a severe genetic condition colloquially referred to as an alpha 1 blood disorder, is formally known as Alpha-1 antitrypsin deficiency (AATD). This inherited condition can raise the risk for serious lung diseases like emphysema and liver diseases such as cirrhosis by disrupting a crucial protective protein.

Bone marrow, the soft tissue at the center of bones, is responsible for producing all of the body's blood cells, including red blood cells, white blood cells, and platelets. When disease or damage disrupts this vital process, it can lead to various serious illnesses that affect bone marrow, profoundly impacting overall health.

Affecting millions worldwide, inherited bleeding disorders are conditions where the body struggles to clot blood properly. This guide explores **what are the three bleeding disorders** most commonly inherited: Hemophilia A, Hemophilia B, and von Willebrand disease, and their crucial differences.

While there is no definitive cure for hemophilia A, the most common type of this inherited bleeding disorder, significant advancements in treatment now allow most affected individuals to live full, productive lives. Over the past few decades, medical science has transformed hemophilia management from a life-limiting condition into a manageable one through innovative therapies.

Did you know that over 100,000 Americans are affected by sickle cell disease? A powerful example of a hemolytic anemia, this inherited blood disorder highlights how genetic factors can cause red blood cells to be prematurely destroyed, leading to a host of health complications.

According to ancient folklore, a baby with salty skin was cursed and destined for a short life. This old wives' tale foreshadowed the modern understanding that salty skin is a telltale symptom of cystic fibrosis (CF), a severe genetic disease.

According to the CDC, approximately 1 in every 365 Black or African American babies is born with sickle cell disease (SCD). Knowing **what are 5 symptoms of a sickle cell crisis** is a critical step for anyone managing or caring for someone with this genetic blood disorder, as early recognition can lead to quicker and more effective intervention.