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Tag: Lof abbreviation

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What does lof mean in medical terms? Understanding its diverse meanings

4 min read
According to large-scale genome sequencing studies, every human carries a significant number of genetic loss-of-function (LOF) variants, suggesting a previously unappreciated level of variation in gene content. This acronym's meaning, however, can be confusing because it refers to completely different concepts depending on the medical specialty. Clarifying exactly what does LOF mean in medical terms is essential for accurate communication between clinicians and patients.