Tag: May hegglin anomaly

May-Hegglin anomaly is a rare autosomal dominant disorder, with fewer than 200 cases reported in medical studies. The condition is defined by a characteristic triad known as **what is the triad of May-Hegglin**, consisting of three specific abnormalities seen in the blood: thrombocytopenia, giant platelets, and leukocyte inclusions.

Giant platelets, also known as macrothrombocytes, are a key feature of several rare inherited bleeding disorders known as macrothrombocytopenias. The most well-known disease associated with giant platelets is Bernard-Soulier syndrome (BSS), which impairs blood clotting and can lead to excessive bleeding.