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Tag: Medical calculation

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What is the 421 fluid requirement?

4 min read
The 4-2-1 rule, a simplified version of the Holliday-Segar formula, is a long-standing method in healthcare used to calculate maintenance intravenous (IV) fluid rates. This critical calculation aims to ensure a patient receives sufficient hydration and electrolytes, making it essential to understand what is the 421 fluid requirement.