What is the concentration of factor VIII in plasma?
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5 min read
The normal concentration of factor VIII in plasma is approximately 0.2 mg/L, or 100 to 200 ng/mL, making it a trace protein in the blood. This coagulation factor plays a critical, but intricate, role in the blood clotting process, with its activity levels typically measured as a percentage of normal pooled plasma. Deviations from this standard range can have significant health implications, most notably in hemophilia A.