Tag: Prostaglandin e2

The hypothalamus, a tiny region of the brain, acts as the body's thermostat, regulating temperature around 98.6°F (37°C). However, during an infection, this set point is deliberately raised through a complex physiological cascade. The core question, "What is the physiological trigger for a fever?" leads directly to understanding this intricate immune and neurological response.

Did you know that a fever is not an illness but a sign that your body's immune system is fighting an infection? This intricate process, which raises your core temperature, is controlled by a specific chemical. But what chemical triggers a fever and how does the body's 'thermostat' respond?

Did you know that a fever is not just a random rise in temperature, but a carefully regulated process controlled by your brain? The substances that raise the temperature setpoint leading to fever are known as pyrogens, which can originate from both inside and outside the body during illness and infection.