Tag: Ryanodine receptor

Malignant hyperthermia (MH) is a rare inherited pharmacogenetic disorder affecting approximately 1 in 100,000 adults, but it can be life-threatening if triggered during surgery. This guide explains exactly what are the triggers of malignant hyperthermia in susceptible individuals.

Affecting approximately 1 in 100,000 adult general anesthesia cases, malignant hyperthermia (MH) is a rare, life-threatening genetic disorder. While most notoriously associated with anesthesia, the question remains: Can stress trigger malignant hyperthermia in susceptible individuals?

Malignant hyperthermia (MH) is a rare inherited condition that causes a severe reaction to certain anesthetic drugs. The first formal description of the disorder occurred in 1960, prompted by a family's history of deadly reactions to anesthesia, raising the question: Where did malignant hyperthermia come from?