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What causes a hemogenic cyst? Exploring the causes of hemorrhagic ovarian cysts

4 min read

Functional ovarian cysts are remarkably common, and an estimated 7% of women experience a symptomatic one at some point in their lives. When one of these normal, fluid-filled sacs accumulates blood, it becomes what is often called a hemogenic or hemorrhagic cyst, a development tied directly to the menstrual cycle.

Quick Summary

Hemorrhagic cysts are caused by bleeding into a functional ovarian cyst, such as a corpus luteum or follicular cyst, due to fragile blood vessels during the normal menstrual cycle. Risk factors include hormonal problems, fertility drugs, and prior history of cysts, though they typically resolve on their own.

Key Points

  • Functional Origin: A hemorrhagic cyst is a functional cyst (corpus luteum or follicular) that has bled internally, and is a result of the normal menstrual cycle.

  • Not Genetic: Unlike some pathological cysts, the cause is typically not genetic but rather a physiological malfunction during ovulation.

  • Common Risk Factors: Hormonal issues, certain fertility drugs like clomiphene, pregnancy, and a history of previous cysts can increase the risk.

  • Self-Resolution: The majority of hemorrhagic cysts will resolve on their own within one to three menstrual cycles.

  • Symptoms Vary: While often asymptomatic, some individuals may experience pelvic pain, bloating, or painful periods; severe pain can indicate a rupture or torsion.

  • When to See a Doctor: Severe or sudden pain, accompanied by nausea, vomiting, or dizziness, requires immediate medical evaluation.

  • Management Options: Treatment ranges from watchful waiting to pain management, hormonal contraceptives to prevent recurrence, or surgery for large or complicated cases.

In This Article

Clarifying the Terminology: Hemogenic vs. Hemorrhagic

First, it's important to clarify the term itself. The search term "hemogenic cyst" is a common misspelling of "hemorrhagic cyst." While "hemogenic" can relate to the production of blood cells, a hemorrhagic cyst is one that contains blood from internal bleeding. For the purposes of this article, we will use the medically accurate term: hemorrhagic cyst.

The Menstrual Cycle and Functional Cysts

The root cause of a hemorrhagic cyst lies within the normal, monthly processes of the menstrual cycle. Each month, one of the ovaries grows a small sac called a follicle, which contains an egg. Normally, about halfway through the cycle, the follicle bursts to release the egg in a process known as ovulation. The most common types of ovarian cysts that can become hemorrhagic are functional cysts, which develop as a result of ovulation.

There are two primary types of functional cysts that can bleed:

  • Corpus Luteum Cyst: After releasing the egg, the ruptured follicle transforms into a temporary, hormone-producing structure called the corpus luteum. Sometimes, the opening where the egg was released seals itself off, and fluid builds up inside. A hemorrhagic corpus luteum cyst occurs when this structure bleeds excessively. This is the most common cause of hemorrhagic cysts.
  • Follicular Cyst: In some cases, the follicle simply fails to rupture and release the egg during ovulation. Instead, it continues to grow, and if it bleeds internally, it becomes a hemorrhagic follicular cyst.

Why Does the Bleeding Occur?

The exact reasons for the bleeding are not always clear, but several factors contribute to it. The cysts are often rich with small, fragile blood vessels. A rupture of one of these vessels leads to blood accumulating within the cyst. The process is also influenced by hormonal fluctuations that occur naturally during the menstrual cycle.

Key Risk Factors for Hemorrhagic Cysts

While the underlying cause is a normal physiological process, certain factors can increase a woman's likelihood of developing a hemorrhagic cyst. These include:

  • Hormonal Issues: Conditions that affect hormonal balance can disrupt the normal ovulatory process, leading to the development of functional cysts. The use of certain fertility drugs, such as clomiphene, is also linked to an increased risk.
  • Pregnancy: Sometimes, a corpus luteum cyst can persist and grow larger during pregnancy, a period of significant hormonal shifts, especially in the first trimester.
  • History of Ovarian Cysts: Women who have had one ovarian cyst are more likely to develop another in the future.
  • Endometriosis: This condition, where endometrial tissue grows outside the uterus, can cause blood-filled cysts called endometriomas. While distinct from typical hemorrhagic cysts, they can appear similar on ultrasound and may contain old blood.
  • Blood Thinners: For individuals on long-term anticoagulant therapy, there is an increased risk of significant bleeding within an ovarian cyst, which can lead to more serious complications.

Differentiating Hemorrhagic Cysts from Endometriomas

While both can contain blood, it is important for diagnosis and treatment to distinguish between a functional hemorrhagic cyst and an endometrioma, which is associated with endometriosis.

Feature Hemorrhagic Cyst Endometrioma
Cause Bleeding within a functional cyst (corpus luteum or follicular) Endometrial tissue implanting and bleeding on the ovary
Associated with The normal ovulatory cycle; often resolves on its own Endometriosis; rarely resolves spontaneously
Ultrasound Appearance Variable, but often shows internal bleeding or a clot Can also contain blood, but often features old, retracted blood clots that appear as characteristic "T2 dark spots" on MRI
Treatment Usually observation or pain management; surgery for complications Surgery is often required, especially if large or causing symptoms

Diagnosis and When to Seek Medical Attention

Diagnosis of a hemorrhagic cyst is typically made via a pelvic ultrasound, which can visualize the cyst and its contents. Most hemorrhagic cysts are asymptomatic and will resolve on their own within a few menstrual cycles with no intervention. However, it is crucial to recognize the symptoms that warrant medical attention:

  • Mild to Moderate Symptoms: Persistent pelvic pain on one side, bloating, painful periods, or pain during intercourse can occur with larger cysts.
  • Emergency Symptoms: Sudden, severe pelvic pain, intense nausea, vomiting, dizziness, lightheadedness, or signs of anemia (pallor, weakness) can signal a ruptured cyst or ovarian torsion. If you experience these, seek immediate medical care.

Treatment and Management

For cysts that are small, asymptomatic, or causing only mild discomfort, the most common approach is conservative management, which means observation. A healthcare provider may recommend a follow-up ultrasound to ensure the cyst has resolved. Pain can be managed with over-the-counter medication.

For individuals with a history of recurrent cysts, hormonal contraceptives may be recommended as they prevent ovulation and therefore reduce the risk of new functional cysts from forming. Surgery may be necessary in cases where:

  • The cyst is large, persistent, or causing severe symptoms.
  • The cyst has ruptured and caused significant internal bleeding.
  • There is a risk of ovarian torsion (a twisting of the ovary).
  • There is concern that the cyst could be malignant.

For more detailed information on ovarian cysts and their management, you can refer to authoritative sources like the Mayo Clinic's guide to ovarian cysts.

Conclusion

In summary, a hemorrhagic cyst is a functional ovarian cyst that has bled internally. The underlying cause is most often a malfunction within the normal monthly menstrual cycle, specifically involving either a corpus luteum or follicular cyst. While most of these cysts are benign and self-resolving, certain risk factors can increase their occurrence. Awareness of the symptoms and knowing when to seek immediate medical attention is essential for proper management and to rule out more serious complications like rupture or ovarian torsion.

Frequently Asked Questions

A functional cyst is a fluid-filled sac that forms during the normal menstrual cycle and is the most common type. A hemorrhagic cyst is specifically a functional cyst (either follicular or corpus luteum) that has experienced bleeding into its interior.

A hemorrhagic cyst is typically diagnosed using a transvaginal or pelvic ultrasound, which can show the cyst's location, size, and the presence of internal bleeding. Other tests, such as a pregnancy test or a blood count, may also be performed.

In most cases, a hemorrhagic cyst does not interfere with fertility. However, if the cyst is associated with conditions like endometriosis or PCOS, or if it grows so large it damages the ovary, it could potentially affect fertility.

Hemorrhagic cysts are overwhelmingly benign (non-cancerous). In very rare cases, cancerous growths can initially present as cysts, but a doctor can often distinguish between them based on characteristics seen on imaging and through blood tests.

No, surgery is not always required. Smaller, asymptomatic cysts often resolve on their own with watchful waiting. Surgery is generally reserved for cases involving persistent severe pain, very large cysts, rupture with significant bleeding, or ovarian torsion.

While there is no guaranteed prevention method, hormonal birth control pills can prevent ovulation and thus reduce the chance of developing functional cysts, including hemorrhagic ones. Managing underlying hormonal conditions can also help.

If a hemorrhagic cyst ruptures, it can cause sudden, severe pelvic pain due to the release of blood and fluid into the abdomen. This may be accompanied by nausea, vomiting, dizziness, or weakness, and requires immediate medical attention to assess the extent of the bleeding.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.