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What causes pain in the epigastric region?

5 min read

According to the American College of Gastroenterology, up to 28% of people in the U.S. experience chronic acid reflux, a common cause of epigastric pain. A wide range of factors, from common indigestion to more serious health conditions, can be responsible for pain in the epigastric region.

Quick Summary

Pain in the epigastric region, located in the upper center of the abdomen, can be caused by various digestive issues like acid reflux, gastritis, and peptic ulcers, as well as conditions affecting the gallbladder or pancreas. Understanding the specific symptoms can help determine the potential cause.

Key Points

  • Location: Epigastric pain is centered in the upper abdomen, below the ribs, and above the belly button.

  • Common Causes: Most cases are caused by common issues like indigestion, acid reflux (GERD), or gastritis.

  • Serious Concerns: Persistent or severe pain can indicate conditions such as pancreatitis, gallstones, or peptic ulcers.

  • Non-Digestive Issues: In rare instances, epigastric pain can be a symptom of a heart attack, especially in women.

  • Diagnostic Process: A doctor will use your symptoms, medical history, and potentially tests like blood work or endoscopy to determine the cause.

  • Treatment Depends on Cause: Treatment can range from lifestyle changes and medication for common issues to surgery for serious conditions.

In This Article

Understanding the Epigastric Region

To understand the causes of epigastric pain, it's essential to know which organs are located in this area. The epigastric region is the central, upper part of your abdomen, situated just below the ribcage and above the belly button. Key organs and structures within or near this region include the stomach, liver, pancreas, duodenum (the first part of the small intestine), and part of the esophagus. Therefore, pain here can be related to a wide array of digestive and non-digestive issues.

Common Digestive Causes

Many cases of epigastric pain are tied to common digestive problems. These issues are often manageable with lifestyle changes and over-the-counter medications.

Indigestion and Dyspepsia

Indigestion, or dyspepsia, is a frequent cause of discomfort in the epigastric area. It often occurs after eating and can cause a feeling of fullness, bloating, or burning. Causes include eating too much, eating too quickly, or consuming greasy, spicy, or acidic foods. Some people experience indigestion due to food sensitivities, such as lactose intolerance.

Gastroesophageal Reflux Disease (GERD)

GERD is a chronic condition where stomach acid frequently flows back into the esophagus. This acid reflux can cause a burning sensation (heartburn), chest pain, and epigastric discomfort. A weak or damaged lower esophageal sphincter is often the culprit, allowing stomach contents to leak upward. Triggers can include certain foods, smoking, and obesity.

Gastritis

Gastritis is the inflammation of the stomach lining. It can be acute (short-term) or chronic (long-term) and causes a gnawing or burning epigastric pain that may improve or worsen with food. Other symptoms include nausea, vomiting, and a feeling of fullness. Causes range from bacterial infections like Helicobacter pylori to excessive alcohol consumption, stress, and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Peptic Ulcer Disease

This condition involves open sores on the lining of the stomach (gastric ulcers) or the duodenum (duodenal ulcers). Peptic ulcers cause a burning epigastric pain that can feel like it's eating a hole in your stomach. The pain may come and go and can be triggered by or relieved by eating. The most common causes are an H. pylori infection and long-term NSAID use.

Serious Underlying Conditions

While many causes are benign, persistent or severe epigastric pain can signal a more serious health issue that requires medical attention.

Pancreatitis

Inflammation of the pancreas, called pancreatitis, can cause severe epigastric pain that often radiates to the back. It may be accompanied by nausea, vomiting, fever, and a rapid pulse. Pancreatitis can be acute or chronic and is often caused by gallstones or excessive alcohol use. Acute pancreatitis requires immediate medical care.

Gallbladder Problems

The gallbladder is a small organ that stores bile. Conditions like gallstones or inflammation (cholecystitis) can cause pain in the epigastric region, sometimes radiating to the right upper abdomen, shoulder, or back. Pain from gallbladder issues is often triggered by fatty meals and can be severe.

Other Significant Causes

  • Hiatal Hernia: This occurs when part of the stomach pushes up through the diaphragm. It can cause acid reflux, chest pain, and epigastric discomfort.
  • Coronary Artery Disease: In rare cases, epigastric pain can be a symptom of a heart attack, especially in women. The pain may feel like indigestion and can be accompanied by shortness of breath, jaw pain, or arm pain.
  • Functional Dyspepsia: This is a condition of chronic indigestion symptoms without an identifiable cause. It includes epigastric pain, burning, early fullness, and bloating.

Comparison of Common Epigastric Pain Causes

Feature Indigestion GERD Gastritis Peptic Ulcer Pancreatitis Gallbladder Issues
Onset After a large/spicy meal Regular, persistent reflux Develops over time (chronic) or sudden (acute) Can be gradual or sudden Sudden, severe attack Sudden, severe attack (after eating)
Sensation Bloating, fullness, mild burning Burning, heartburn, chest pain Gnawing, burning, dull ache Gnawing, burning pain, sometimes relieved by eating Severe, persistent pain that radiates to back Sharp, cramping pain in upper abdomen
Location Mid-to-upper abdomen Behind the breastbone, extending to throat Upper abdomen, central Upper abdomen, central Upper abdomen, often radiating to back Upper right or central abdomen
Associated Symptoms Belching, nausea Nausea, sore throat, bad breath Nausea, vomiting, loss of appetite Nausea, vomiting, weight loss, bloating Nausea, vomiting, fever Nausea, vomiting, jaundice
Key Triggers Overeating, fatty/spicy foods Fatty foods, caffeine, large meals NSAIDs, alcohol, H. pylori H. pylori, NSAIDs, alcohol Gallstones, alcohol abuse Fatty meals

Diagnosis and Treatment

Determining the root cause of epigastric pain is crucial for effective treatment. A healthcare provider will typically start with a physical exam and discuss your symptoms and medical history. They may order diagnostic tests to rule out serious conditions, including:

  • Blood tests: To check for infection, inflammation, or liver/pancreatic issues.
  • Imaging tests: Ultrasounds, CT scans, or X-rays can help visualize organs.
  • Endoscopy: An upper endoscopy may be used to view the esophagus, stomach, and duodenum directly.
  • H. pylori tests: To check for the presence of the bacteria.

Treatment varies widely depending on the diagnosis. For mild cases, simple lifestyle changes such as eating smaller meals, avoiding trigger foods, and managing stress may be enough. Over-the-counter antacids or acid reducers can also provide relief. More serious conditions may require prescription medications, such as antibiotics for an H. pylori infection or stronger acid-blocking drugs for ulcers or GERD. In some severe cases, such as with gallstones or a complicated hiatal hernia, surgery may be necessary.

When to See a Doctor

While occasional indigestion is normal, persistent or severe epigastric pain should be evaluated by a healthcare professional. Seek immediate medical attention if you experience pain along with severe symptoms, such as difficulty breathing, vomiting blood, black or tarry stools, a high fever, or intense chest pressure. For more information on digestive health, you can visit the National Institute of Diabetes and Digestive and Kidney Diseases website.

Conclusion

Epigastric pain is a common symptom with a multitude of potential causes, ranging from simple indigestion to complex medical conditions affecting the stomach, pancreas, or gallbladder. Paying close attention to the characteristics of the pain and any accompanying symptoms can provide valuable clues. While many cases resolve on their own with minor adjustments, understanding when to seek professional medical advice is essential for proper diagnosis and treatment. By taking proactive steps and consulting with a doctor when necessary, you can effectively manage epigastric pain and maintain your digestive health.

Frequently Asked Questions

Epigastric pain can manifest in different ways depending on the cause. It can feel like a dull ache, a sharp or burning sensation, or cramping. The pain may be constant, intermittent, or worse after eating.

Yes, stress can be a contributing factor to epigastric pain. Emotional and physical stress can increase the production of stomach acid and affect digestion, leading to conditions like gastritis or worsening symptoms of GERD and peptic ulcers.

While it's rare, epigastric pain can sometimes be a sign of a heart attack, especially in women. If epigastric pain is accompanied by other symptoms like shortness of breath, chest pressure, sweating, or pain radiating to the jaw or arm, seek immediate medical attention.

Both can cause epigastric pain, but a peptic ulcer often causes a more intense, burning or gnawing sensation that may be relieved or triggered by eating. Indigestion is usually a milder, more general discomfort often related to a recent meal. A doctor's diagnosis is required to confirm.

Yes, many foods can act as triggers. Common culprits include spicy, fatty, or acidic foods, as well as caffeine and alcohol. Avoiding these foods can often help manage pain caused by indigestion, GERD, and gastritis.

You should see a doctor if your epigastric pain is severe, persistent, or is accompanied by other worrying symptoms such as vomiting blood, black or tarry stools, difficulty swallowing, or unexplained weight loss.

Functional dyspepsia is a diagnosis given for chronic indigestion and epigastric pain when no structural or metabolic cause can be found after testing. The exact cause is unknown but is thought to involve factors like heightened nerve sensitivity in the digestive tract.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.