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What does pathological mean in medical terms?

4 min read

Approximately 7,000 to 8,000 named rare diseases have been identified, many of which can be described by their pathological characteristics. The term pathological in medical terms refers to conditions, processes, or behaviors caused by or indicative of a disease, distinguishing them from what is considered normal or healthy.

Quick Summary

In medicine, 'pathological' describes a disease-related state, condition, or process, whether it refers to bodily changes, symptoms, or mental behaviors. It signifies an abnormality that deviates from a healthy standard, often rooted in the study of disease itself.

Key Points

  • Pathological Definition: Refers to any condition, process, or behavior caused by or indicative of a disease.

  • Pathological vs. Physiological: Contrast the abnormal, disease-related state (pathological) with normal, healthy body functions (physiological).

  • Diverse Applications: The term applies to physical changes (e.g., tissue damage), symptoms (e.g., fever), and mental health issues (e.g., pathological lying).

  • Diagnostic Tool: Pathologists use the term to describe findings from lab work, biopsies, and other tests to help diagnose diseases.

  • Examples: Includes specific cases like a pathological fracture in orthopedics, a pathological finding in a tissue biopsy, or a pathological heart murmur in cardiology.

In This Article

Understanding the Core Meaning of Pathological

At its heart, the word pathological is derived from the Greek word pathos, meaning 'suffering' or 'disease,' and logia, meaning 'the study of.' It is directly linked to the field of pathology, the medical specialty that focuses on the causes and effects of disease.

When a medical professional uses the term, they are indicating that a particular finding or symptom is not part of the body's normal function. Instead, it is a sign or a result of an underlying illness. This applies to everything from changes seen in tissue under a microscope to physical symptoms a patient might experience.

Pathological vs. Physiological

To grasp the full meaning of 'pathological,' it is helpful to contrast it with its counterpart, 'physiological.'

Physiological refers to the normal, healthy functioning of the body. For example, a temporary rise in heart rate after exercise is a normal, physiological response. The heart is working as it should to meet the body's demands.

A pathological heart rate, however, would be a consistently high heart rate unrelated to exertion, which could be a sign of an underlying heart condition. This distinction is crucial for doctors when diagnosing and treating conditions.

Types of Pathological Findings

Pathological findings can be categorized in several ways, each describing a different aspect of a disease process. Understanding these types helps in appreciating the breadth of the term.

  • Pathological anatomy: This refers to changes in the body's structure due to disease. An example is the thickening of artery walls in atherosclerosis.
  • Pathological physiology: This describes how disease alters the function of the body's organs and systems. A classic example is the impaired insulin production in type 1 diabetes.
  • Pathological signs: These are objective signs of disease that can be observed and measured by a doctor. A rash, swelling, or a fever are all pathological signs.
  • Pathological symptoms: These are subjective experiences of the disease reported by the patient, such as pain, fatigue, or nausea.
  • Pathological behavior: In psychology, this describes a behavior pattern that is considered abnormal and indicative of a mental health condition, such as a pathological liar.

Detailed Examples in Medical Context

To illustrate the concept further, consider these specific examples from various medical fields:

  1. Cardiology: A patient with a heart murmur might have a pathological heart sound. A normal, or physiological, heart sound is the classic 'lub-dub.' A murmur, an extra sound, indicates an issue with blood flow and is therefore pathological.
  2. Orthopedics: A pathological fracture is a bone break that occurs not because of a significant trauma, but because the bone has been weakened by an underlying disease, such as osteoporosis or a tumor.
  3. Pathology (lab work): When a biopsy is taken, the pathologist examines the tissue for pathological changes, such as the presence of cancer cells. These are changes that differ significantly from healthy tissue cells.
  4. Oncology: The term can describe a tumor. A pathological tumor, or lesion, is a tissue growth that is a result of disease, not normal tissue growth.

Comparison: Pathological vs. Non-Pathological

Feature Pathological (Diseased) Non-Pathological (Normal)
Cause Due to a disease or illness. A normal biological function or healthy state.
Nature Abnormal, unhealthy, or indicative of disease. Expected, healthy, or within a normal range.
Heart Rate Consistently high heart rate at rest (e.g., tachycardia). Temporary increase in heart rate during exercise.
Bone Fracture A fracture caused by a minor injury in weakened bone. A fracture caused by significant trauma in a healthy bone.
Weight Fluctuation Extreme, unexplained weight loss or gain. Gradual weight change due to diet or lifestyle adjustments.
Mental State Extreme, uncontrollable behaviors (e.g., pathological lying). Occasional, situational lying (though undesirable, not necessarily a disorder).

The Role of Pathology in Diagnosis

The work of a pathologist is central to identifying pathological conditions. Using tools like microscopes and chemical tests, they analyze samples of blood, tissue, and other bodily fluids to pinpoint the changes caused by disease. Their findings inform the diagnosing physician, providing the concrete evidence needed to confirm a diagnosis.

For example, if a doctor suspects a patient has an infection, a blood test showing an abnormally high white blood cell count would be a pathological finding. The pathologist would identify this, and the doctor would use that information to prescribe a course of action.

Pathological Findings in Mental Health

Beyond physical diseases, the term also applies in a psychiatric context. A pathological behavior is one that is compulsive, extreme, and symptomatic of a mental health disorder. For instance, a pathological liar cannot control their impulse to lie, even when the truth would be more beneficial. This is distinct from someone who tells occasional lies. This distinction helps mental health professionals differentiate between typical human behavior and clinically significant disorders. The World Health Organization is a leading authority on medical and mental health classifications, outlining such criteria in resources like the ICD-11.

Conclusion

In summary, the term pathological in medical terms serves as a fundamental descriptor for anything abnormal or disease-related. It is a word that distinguishes healthy, normal processes from those caused by an illness. From a lab report detailing cellular changes to a clinician's description of a patient's symptoms, understanding this term is key to comprehending the language of medicine and the process of diagnosis.

Frequently Asked Questions

Normal, or physiological, refers to the expected, healthy function of the body. Pathological refers to an abnormal state or process that is caused by or indicative of a disease.

Yes, it is possible. Some pathological conditions, especially in their early stages, may not present any noticeable symptoms but can be detected through medical tests, such as a lab test revealing abnormal cell growth.

A pathological finding is an observation made by a doctor or a pathologist during a medical examination, test, or procedure that is indicative of a disease. This could be anything from an abnormal lab result to the appearance of a tissue sample.

Yes, 'pathological liar' is a term used in a psychological context to describe a person who compulsively and habitually lies. This behavior is considered a symptom of an underlying mental health disorder rather than a normal behavioral trait.

Absolutely. The changes and symptoms caused by an infectious disease, such as a fever caused by a virus or bacterial presence, are described as pathological.

A biopsy is the procedure of taking a tissue sample, which is then sent to a pathologist. The pathologist examines the tissue to identify any pathological changes, such as cancer cells, and reports their findings to the doctor.

A pathological process is the sequence of events that occurs in the body during the development of a disease. For example, the inflammation of an artery leading to plaque buildup is a pathological process in the development of heart disease.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.