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Whose blood cannot be donated? A comprehensive guide to eligibility

4 min read

According to the American Red Cross, only about 3% of eligible people in the U.S. donate blood each year. While many healthy individuals can give, certain medical conditions, recent travel, and specific lifestyle factors determine whose blood cannot be donated for safety reasons.

Quick Summary

The ability to donate blood depends on strict eligibility criteria designed to protect both the donor and the recipient, with reasons ranging from chronic illnesses like HIV and certain cancers to temporary factors such as recent tattoos, travel, or medication use.

Key Points

  • HIV/AIDS: A positive HIV test at any time is a permanent deferral for blood donation.

  • Hepatitis B or C: A history of these viral infections leads to a permanent ineligibility to donate blood.

  • Blood cancer: A history of leukemia or lymphoma results in a permanent deferral, while other cancers may require a temporary waiting period.

  • Recent tattoo or piercing: Receiving a tattoo or piercing from an unregulated facility typically requires a 3-month waiting period before donating.

  • Travel to malaria zones: Individuals who have traveled to a malaria-risk area may have to wait 3 months or more before they can donate blood.

  • Specific medications: Certain drugs, like blood thinners and some acne medications, can affect eligibility and require a waiting period.

  • Good health is a must: Donors must be in good health and free of active infections, colds, or fevers on the day of donation.

In This Article

Who is ineligible to donate blood?

Blood donation organizations, such as the American Red Cross and Vitalant, follow strict guidelines set by the U.S. Food and Drug Administration (FDA) to ensure the safety of the blood supply. These guidelines are in place to protect the health of both the donor and the recipient. Eligibility is a complex topic, and deferrals can be permanent or temporary, based on various health, travel, and behavioral factors.

Medical conditions that prevent blood donation

Certain health issues can permanently or temporarily disqualify an individual from donating blood. These are often related to the risk of transmitting infectious diseases or to the donor's own health and safety. The following are some of the most common medical reasons for deferral:

  • HIV/AIDS: Individuals who have ever tested positive for HIV or have AIDS are permanently deferred from donating blood. This is an absolute rule to prevent transmission of the virus.
  • Hepatitis: A history of viral hepatitis B or C, especially after the age of 11, can result in permanent deferral. Recent exposure to hepatitis can also lead to a temporary deferral.
  • Certain types of cancer: A history of blood cancers, such as leukemia or lymphoma, is a permanent deferral. Other types of cancer may be acceptable if treated successfully and a specific time has passed since the end of treatment, typically 12 months. However, individuals should consult their local blood center for specific guidelines.
  • Creutzfeldt-Jakob Disease (CJD): A fatal brain disease, CJD can be transmitted through blood. Individuals who have ever received a dura mater (brain covering) transplant or have a blood relative with genetic CJD are permanently deferred. Travel or residence in certain European countries during specific timeframes may also result in a deferral.
  • Serious heart conditions: Individuals with certain heart conditions, such as a history of heart attacks, angina, or irregular heart rhythms, may have restrictions. A specific waiting period, often 6 months, may be required after a heart-related event or surgery.
  • Bleeding disorders: Conditions like hemophilia that affect blood clotting make a person ineligible to donate.
  • Active infection or fever: Donors must be in good health and feeling well on the day of donation. Those with a cold, flu, sore throat, or fever are temporarily deferred until symptoms are resolved.
  • Pregnancy: Expectant mothers cannot donate blood. A waiting period of 6 weeks is typically required after childbirth.

Lifestyle and behavioral factors for deferral

Eligibility is not solely based on medical history. Personal behaviors and recent activities also play a significant role in determining if someone can safely donate.

  • Recent tattoos and piercings: If a tattoo or piercing was received in the last three months in a state that does not regulate tattoo facilities, a deferral period is usually enforced. The deferral period helps ensure that any potential infection has cleared. The specific waiting time can vary by state and blood center.
  • Intravenous drug use: Anyone who has used non-prescription injection drugs, steroids, or anything not prescribed by a doctor within the last 3 months is deferred. In many cases, a history of injection drug use can lead to a permanent deferral due to the high risk of infectious disease transmission.
  • Exposure to infectious disease: Recent sexual contact with someone with HIV or hepatitis B or C can result in a 3-month deferral. Individuals who have received a blood transfusion in the last 3 months are also temporarily deferred.
  • High-risk behaviors: Engaging in sex in exchange for money or drugs will result in a deferral.
  • Medications: Certain medications can affect blood donation eligibility, including some antibiotics, blood thinners like warfarin, and medications used for severe acne, hair loss, or HIV prevention (PrEP/PEP). The deferral period varies depending on the specific medication.

Travel restrictions and exposure risks

Travel to certain areas of the world can expose individuals to infectious diseases that could be passed on through blood transfusion. Organizations adhere to guidelines from the Centers for Disease Control (CDC) to assess these risks.

  • Malaria risk areas: Individuals who have traveled to a country with a high risk of malaria may be deferred for a period, typically 3 months after their return. The deferral can be longer for those who have lived in these areas for an extended period.
  • Variant Creutzfeldt-Jakob Disease (vCJD) risk: Based on specific travel and residence periods in certain European countries, individuals may face a deferral due to the risk of transmitting vCJD, also known as "mad cow disease".

Comparison of Common Deferral Categories

Deferral Reason Permanent Deferral Temporary Deferral Notes
HIV positive test Yes No An absolute permanent deferral.
Hepatitis B/C (positive test) Yes No Permanent after testing positive, especially after age 11.
Certain cancers Yes (Leukemia/Lymphoma) Yes (Other types) Permanent for blood cancers; temporary (12+ months) for others.
Medications (e.g., blood thinners) No Yes Waiting periods vary; depends on specific medication.
Recent tattoo/piercing No Yes (3 months) If not done in a state-regulated facility using sterile needles.
Travel to malaria-risk area No Yes (3 months) Waiting period varies depending on location and duration of stay.
Recent blood transfusion No Yes (3 months) Waiting period after receiving blood products.

Conclusion

Blood donation is a vital and generous act, but strict eligibility criteria are essential for maintaining the safety of the national blood supply. The question of whose blood cannot be donated is answered by a complex set of rules related to medical history, lifestyle, and recent activities. While deferral can be disappointing, it is crucial for protecting the health of both the donor and the recipient. For the most accurate and up-to-date information on eligibility, always check the guidelines of your local blood donation center or visit the American Red Cross website.

Frequently Asked Questions

Yes, you can typically donate blood if your high blood pressure is well-controlled with medication and your reading is below 180/100 at the time of donation.

Individuals with diabetes are generally eligible to donate blood, provided their condition is well-controlled with medication or diet. If on bovine-sourced insulin, specific restrictions may apply.

The deferral period is usually 3 months if the tattoo or piercing was received in an unregulated facility or state. It is best to check with your local blood center.

Yes, travel to certain regions with a high risk of diseases like malaria or certain types of Creutzfeldt-Jakob Disease can result in a temporary or permanent deferral.

No, if you have symptoms of a cold, flu, or other acute infection, you must wait until you are fully recovered and symptom-free before donating.

Yes, certain medications, including blood thinners, oral and injectable HIV prevention drugs (PrEP/PEP), and some acne medications, can temporarily or permanently disqualify you.

Individuals who have ever tested positive for HIV are permanently deferred to prevent the potential transmission of the virus through the blood supply, ensuring maximum safety for recipients.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.