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Why do people wake up screaming from anesthesia?

4 min read

Emergence delirium, a state of confusion and agitation as anesthesia wears off, affects a significant number of patients, with studies reporting incidents in over 20% of some adult surgical groups. This phenomenon helps explain why people wake up screaming from anesthesia, a distressing experience for everyone involved.

Quick Summary

The sudden confusion and agitation seen when a patient awakens from anesthesia is known as emergence delirium, and it occurs due to the differential effects of anesthetics on brain function during recovery.

Key Points

  • Emergence Delirium: The medical term for waking up confused, agitated, or screaming after anesthesia due to the brain recovering unevenly.

  • Transient Episode: While alarming, the episode is typically brief, lasting only a few minutes, and often forgotten by the patient upon full recovery.

  • Multiple Risk Factors: The likelihood of experiencing ED is influenced by factors including age (especially young children and older adults), preoperative anxiety, and certain anesthetics or surgical types.

  • Not Awareness: Emergence delirium is distinct from anesthetic awareness, as the patient does not remember the event. It is a state of confusion, not a state of consciousness during surgery.

  • Proactive Management: Risk can be reduced by managing anxiety, ensuring adequate pain control, and creating a calm recovery environment.

  • Caregiver Role: Reassuring the patient calmly, providing familiar objects, and ensuring safety are crucial actions for family and medical staff.

In This Article

Understanding Emergence Delirium

Emergence delirium (ED), sometimes called emergence agitation, is a well-documented phenomenon that occurs in the immediate post-operative period. It involves a patient exhibiting an altered state of consciousness as they transition from being fully anesthetized to regaining full awareness. While some patients may wake up calmly and lucidly, others may appear disoriented, frightened, and demonstrate agitated, uncharacteristic behavior, which can include yelling or screaming. Though it can be alarming, it is typically a short-lived complication that resolves on its own within a few minutes to an hour.

The Neurological Disconnect

The precise cause of emergence delirium is not completely understood, but current research suggests it is linked to the complex way different parts of the brain recover from anesthesia. Volatile anesthetic agents affect different areas of the central nervous system at varying rates. During emergence, a patient's sensory and motor functions may return before their cognitive and emotional control centers are fully back online. This creates a temporary disconnect where the patient can perceive their environment and physical sensations, such as pain or the discomfort of a breathing tube, but lacks the higher-level cognitive ability to process these stimuli rationally. The result can be a panicked, flight-or-fight response, leading to behaviors like screaming and thrashing.

Risk Factors for Emergence Delirium

Certain factors can increase the likelihood of experiencing ED. The risk profiles differ somewhat between adult and pediatric populations.

Pediatric Risk Factors

  • Younger age: Emergence delirium is particularly common in children between the ages of two and five.
  • Preoperative anxiety: The stress and fear a child feels before surgery can be a significant contributing factor.
  • Type of anesthesia: The use of certain low-solubility volatile anesthetics, such as sevoflurane and desflurane, has been associated with a higher incidence of ED.
  • Type of surgery: Ear, nose, and throat (ENT) and eye surgeries are often cited as procedures with a higher risk for ED in children.

Adult Risk Factors

  • Age extremes: While children are at high risk, adults on both ends of the age spectrum (those younger than 40 and older than 65) also show an increased risk.
  • Pre-existing conditions: A history of psychiatric problems, cognitive impairment, or substance abuse can increase the risk.
  • Type and duration of surgery: Emergency operations and longer surgical procedures are associated with higher rates of ED.
  • Invasive devices: Waking up with a breathing tube, urinary catheter, or other invasive device can be distressing and a significant trigger for agitation.
  • Postoperative pain: Uncontrolled pain is a major contributor to agitation and confusion during emergence.

Distinguishing Emergence Delirium from Related Conditions

It is crucial to differentiate emergence delirium from other post-anesthetic complications to ensure appropriate care. Here is a comparison of ED and postoperative delirium (POD), which can sometimes be confused.

Feature Emergence Delirium Postoperative Delirium
Onset Occurs immediately as the patient wakes from anesthesia. Develops 24 to 72 hours after surgery.
Duration Typically short-lived, resolving within minutes to an hour. Can last for days, weeks, or even months.
Symptoms Often hyperactive behavior: screaming, thrashing, confusion, disorientation, not recognizing familiar faces. Can be hyperactive (agitation, hallucinations) or hypoactive (lethargy, withdrawal).
Memory Patients usually have no memory of the episode upon full recovery. Patients may have fragmented memories of the experience.
Population Affects both children and adults, but is more common in children aged 2-5. Most prevalent in older adults and those with pre-existing cognitive issues.

It is also important to distinguish ED from anesthetic awareness. With awareness, the patient remembers and can later recall conversations or events that occurred during the surgery. In contrast, patients with ED are in a transitional, disoriented state and do not form new memories. While a bad dream during anesthesia is a possibility, the intense, non-purposeful thrashing and screaming of ED are distinct.

Management and Coping Strategies

Managing emergence delirium involves a multi-pronged approach focused on patient safety and comfort.

For the Patient

  1. Preparation and Communication: Before surgery, discuss potential ED with the anesthesiologist and care team. Ensure they are aware of any pre-existing anxiety or risk factors.
  2. Pain Management: Adequate pain control is critical, as untreated pain can exacerbate confusion and agitation.
  3. Familiar Comforts: Bringing a familiar object, such as a favorite blanket or photograph, can help ground the patient in the recovery room.

For Caregivers and Medical Staff

  • Provide Reassurance: Remaining calm and speaking in a soothing voice can help comfort the patient. Remind them where they are and why.
  • Optimize the Environment: A calm, quiet recovery space with dim lighting can help reduce sensory overload. Providing glasses or hearing aids can also help orient the patient.
  • Ensuring Safety: The patient's immediate safety is the top priority. Staff will ensure the patient does not pull out medical lines or harm themselves. In severe cases, mild sedation may be necessary to prevent injury.

Conclusion

Waking up screaming from anesthesia is a symptom of emergence delirium, a temporary neurological state resulting from the way the brain recovers from anesthetic agents. While distressing, it is generally harmless, especially in children, and the patient typically has no memory of the event. Understanding the risk factors and employing management strategies focused on comfort, reassurance, and safety can help mitigate episodes. It is important to know that this is a recognized medical phenomenon, not a sign of a serious, long-term problem for most patients.

For more in-depth medical information on the neural mechanisms behind anesthesia and emergence, please consult authoritative medical resources such as the National Institutes of Health.

Frequently Asked Questions

Yes, for some patients, particularly young children and older adults, waking up with signs of agitation, crying, or even screaming is a temporary and recognized side effect known as emergence delirium. It is a sign of confusion, not lasting distress.

Emergence delirium is a state of altered mental function that occurs as a person wakes up from general anesthesia. It's caused by the uneven recovery of different parts of the brain and can lead to disorientation, emotional outbursts, and sometimes thrashing or screaming.

No, most patients who experience emergence delirium have no memory of the agitated state after they have fully recovered. The confusion and lack of awareness during the episode prevent the formation of coherent, lasting memories.

For the majority of patients, particularly children, emergence delirium does not cause long-term psychological problems. The effects are typically temporary. However, older adults with pre-existing cognitive issues are at a higher risk of developing more lasting postoperative cognitive dysfunction.

Risk factors include extremes of age, high anxiety before surgery, certain types of anesthetics (sevoflurane and desflurane), certain types of surgery (ENT, eye), preexisting cognitive or psychiatric issues, and the presence of invasive medical devices like breathing tubes.

Emergence delirium happens immediately after anesthesia and is usually brief. Post-operative delirium, on the other hand, can occur one to three days after surgery and last much longer. It is more common in older adults and is a more complex condition.

The best thing a family member can do is remain calm and reassuring. Speak in a gentle voice, remind them where they are, and ensure they have familiar items like glasses or hearing aids to help orient them.

While uncontrolled postoperative pain can contribute to agitation, screaming during emergence is not always a direct sign of severe pain. It is more often a result of confusion and disorientation as the anesthetic wears off, exacerbated by unfamiliar sensations.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.